A new platform identifies which genes drive particle assembly to engineer cells that yield more potent delivery vehicles.

Companies are adopting diverse approaches to reducing unwanted toxicities associated with cell and gene therapy.

Genetic defects are exceedingly common, which is not surprising considering just how many cells make up our bodies, including our reproductive cells. While most of these defects have no or only minor ...

Two papers published in The New England Journal of Medicine highlight the potential of gene editing for treatment of sickle ...

CAR T cells are patient-derived, genetically engineered immune cells. They are "living drugs" and constitute a milestone in modern medicine. Equipping T cells, a key cell type of the immune system, ...

Gene editing has emerged as a powerful approach for targeting the genetic causes of disease, but getting the editing ...

Over the past century, worldwide consumption of food-animal products such as meat, milk, and eggs has steadily grown due to increases in global population and per capita income that fuel demand for ...

Cells contain a blueprint in the form of DNA that dictates what they can make. This blueprint is converted into a message (mRNA), which is then converted into a protein. Although DNA remains the same ...

An understanding of the origin and dynamics of heritable genetic variation within classical animal breeding programs is needed to provide the context for understanding the contributions and concerns ...