A team of researchers has uncovered a key cellular mechanism that affects the function of mRNA vaccines and therapeutics. Their study provides the first comprehensive understanding of how mRNA ...

From the paper: ""Ketone bodies are janitors of damaged proteins, chaperoning away molecular waste so organisms can operate ...

Biological ageing is a highly heterogeneous process that cannot be captured by chronological age alone. Emerging evidence highlights the central role of ...

Researchers have for the first time identified degeneration-associated 'molecular markers' -- observable changes in cells and their gene-regulating networks -- that are shared by several forms of ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

The mystery of how cancers build up resistance mechanisms and evade the treatments that should have destroyed them is a hugely pressing question. Overcoming cancer treatment resistance—a phenomenon ...

Electron micrographs show typical microglia in the prefrontal cortex of a 92-year-old healthy female (left) and dark microglia a 91-year-old female patient with Alzheimer’s disease (right). Microglia, ...

Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

New research from scientists at the University of Washington (UW) School of Medicine and Duke University describes how cellular RNA helps regulate antiviral signaling as part of the immune response ...

Much like humans generate mountains of garbage, our cells are constantly discarding proteins that are damaged or no longer needed. The cellular waste disposal system called the proteasome is best ...