A study reveals chromatin moves in constrained or freer patterns, shaping how genes contact regulatory elements and repair ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

DNA inside the nucleus is not packed as a rigid regular fiber-linker histone H1 dynamically binds and loosely "glues" nucleosomes together, creating a dynamic, fluid organization that can still ...

A recent study has shed light on the transcriptional regulatory mechanisms of Penicillium expansum, the fungal culprit behind blue mold disease in fruits. By mapping chromatin accessibility at ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can also lead to cancer and other diseases. To better understand how chromatin ...

Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...

On the left is a snapshot of single histone molecules (red) inside a cell nucleus (dotted line). On the right, we see the trajectories of these molecules’ movement over time. The colors show the path ...