Researchers discovered that disrupted PTH1R signaling drives abnormal cementum growth and tooth-bone fusion in adult ...

Amyotrophic lateral sclerosis (ALS) is a serious and usually fatal neurodegenerative disorder in which motor neurons deteriorate and die. The disease causes a loss of movement that eventually affects ...

Mitochondrial defects are associated with the development of diseases such as type 2 diabetes (T2D). Studies in mice and in human tissues, by researchers at the University of Michigan, have now found ...

The Wei lab is interested in the regulation of cell signaling and tissue homeostasis by metalloproteinases and other proteins in development and disease. Project 1. The mechanisms of neural crest ...

CYR61, cysteine-rich angiogenic inducer 61; FT, factors of transcription; LATS, large tumor suppressor; MOB, mob kinase activator; MST, mammalian sterile 20-like ...

Calcium is widely known for its role in maintaining strong bones and teeth, but it is also one of the body's most important ...

A growing body of preclinical research points to the TIE2 receptor and its angiopoietin ligands as a promising drug target for brain blood vessel defects, including arteriovenous malformations, venous ...