In about one out of every 1,000 pregnancies, the neural tube, a key nervous system structure, fails to close properly.

Neural tube defects, such as Spina bifida, are one of the leading congenital disorders (affecting about one in 1,000 live births worldwide) and are associated with the junctional neurulation. Though ...

The quail is a small, unassuming bird that glides rather than flies and prefers to hide under bushes than to perch on top of ...

How does the neural tube close? A new study uses physics-based modeling to reveal the actin "purse-string" mechanism and cellular coordination that prevents spina bifida.

Precursor cells in the embryonic neural tube are organized in a specific striped pattern which depends on the signals they receive (left). Lehr and colleagues recreated this pattern in a cell culture ...

Their findings, recently reported in the journal Nature, overturn longstanding assumptions in developmental biology and could change the way scientists think about treatments for a variety of ...

When do peripheral nerves develop? Researchers used "mosaic barcodes" to prove that neural crest cells commit to their ...

In the field of developmental neurobiology, accurate and ordered regulation of the cell cycle and apoptosis are crucial factors contributing to the normal formation of the neural tube. Preliminary ...

A scientific breakthrough that could lead to the eradication of deadly neural tube defects in unborn babies has been ...

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...