In vertebrates, unfertilized eggs are arrested at metaphase of meiosis II by Emi2, a direct inhibitor of the APC/C ubiquitin ligase. Two different ubiquitin-conjugating enzymes, UbcH10 and Ube2S, work ...
When producing our germ cells – egg and sperm – a special feature is required in the cell division process: Since male and female germ cells fuse during fertilization, the chromosome set of our ...
The process by which an immature oocyte develops into a fertilizable gamete is known as oocyte maturation. In most animals, the mature oocytes or eggs are arrested in the meiotic cell cycle awaiting ...
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