Researchers showed how what appears to be a tangle of DNA is actually organized into a structure that coordinates thousands of genes to form a sperm cell. The work, published as two papers in Nature ...

Before cells can divide by mitosis, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Scientists have until now ...

The genome is the complete set of DNA within a cell, encompassing protein-coding genes, non-coding elements and vast tracts of intergenic sequence. In eukaryotes, this information is packaged into ...

CHICAGO --- In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed ...

Certain epigenetic modifications can directly control how genetic material is packed in the nucleus, RIKEN researchers have ...

Researchers at The University of Texas at Austin have uncovered key principles that govern how DNA "origami" structures fold, ...

Chemists have found a new way to determine 3D genome structures, using generative AI, that can predict thousands of genome structures in minutes, making it much speedier than existing methods for ...

They were hardly modest, these two brash young scientists who in 1953 declared to patrons of the Eagle Pub in Cambridge, England, that they had "found the secret of life." But James Watson and Francis ...

Before cells can divide, they first need to replicate all of their chromosomes, so that each of the daughter cells can receive a full set of genetic material. Until now, scientists had believed that ...

New work from UC Davis and the University of Utah shows how the 3D structure of DNA inside a germ cell commits it to develop into a sperm cell. The discovery could improve understanding of fertility ...