As blood stem cells age, their lysosomes become overactive and damaged, triggering inflammation and weakening the body’s ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

The colorful dots at the center are cytotoxic granules used to destroy infected or cancerous cells. Credit: F. Lemaitre @ ...

Scientists want to know what causes B cells — which direct T cells to attack cancer — to malfunction and how they can be ...

The immune system is a complex response of various cells that detect and elicit mechanisms to eliminate disease. This ...

During infection or cancer, cytotoxic T lymphocytes attach to their target and establish an exchange zone known as the immune ...

Cancer cells can disarm the immune system not just by hiding from it, but by actively reprogramming nearby immune cells into a suppressed state. This previously unrecognized molecular interaction, ...

St. Jude Children's Research Hospital scientists have discovered how tumors disable immune "gatekeeper" cells that alert the rest of the immune system to the presence of cancer - and how restoring ...

Activated immune cells secrete tiny capsules bearing DNA that can enter other immune and tumor cells to stimulate the body's defense systems, according to a study led by investigators at Weill Cornell ...