Diabetes. 2006;56(3):594-603. Cellular and morphological characteristics of islets and quantification of cell death (including apoptosis and necrosis). For normoxic and hypoxic conditions, ...

Researchers from the University of Geneva (UNIGE) and Geneva University Hospitals (HUG) have reached a significant advance in ...

Islets of Langerhans and β-cell isolation constitute routinely used cell models for diabetic research, and refining islet isolation protocols and cell quality assessment is a high priority. Numerous ...

BM stem cells may have regenerative effects on islet function through angiogenesis. Human islets (100 islet equivalent/mL) were cultured alone (control) or co-cultured (experimental group) with whole ...

The currently approved islet-transplant method infuses islets into a vein in the liver. This invasive procedure requires the long-term use of immune-suppressing drugs to prevent islet rejection, ...

Detailed characterization of human pancreatic islets is key to elucidate the pathophysiology of all forms of diabetes mellitus, including its most common form known as type 2 diabetes (T2D). However, ...

A team of international scientists has made a major leap forward in diabetes research by successfully 3D printing functional human islets using a novel bioink. Presented today at the ESOT Congress ...

In culture and after transplantation, the oxygen supply of islets and nutrients depends solely on diffusion. The pO 2 level may be sufficiently high throughout the transplanted islets to maintain cell ...