Laser capture microdissection (LCM) is emerging as a premier technology with a point-and-shoot capability designed to rapidly isolate single cells or unique multicellular structures from complex ...

Solid tumors are composed not only of tumor cells but also of stromal nonneoplastic cells. In whole tumor samples, stromal cells retaining their alleles may therefore obscure detection of loss of ...

Laser microdissection instruments, such as the CellCut Plus ® and SmartCut Plus ® from Olympus, have proven to be excellent research and forensic tools. This is because they provide precise extraction ...

LMD allows researchers to target a specific cell—or even chromosome—and excise it from the cells that surround it on a slide, or in some cases, on a culture dish. 1 Researchers can use some LMD ...

This is a preview. Log in through your library . Abstract Iron ranks fourth in the sequence of abundance of the elements in the Earth's crust, but its low bio-availability often limits plant growth.

Understanding genomic variation in the context of cancer is paramount to identifying disease drivers and informing personalized treatment for patients. Tumor heterogeneity presents a challenge in ...

Interactions of breast cancer cells with the microenvironment of the human bone marrow No significant financial relationships to disclose. This is an ASCO Meeting Abstract from the 2009 ASCO Annual ...

Microdissection is a method to isolate individual or group of cells from tissue sections. This results in preparation of samples of homogeneous cell types that allows performance of sensitive and ...

Neglecting tissue heterogeneity during the analysis of microRNA (miRNA) levels results in average signals from an unknown mixture of different cell types that are difficult to interpret. Here we ...

Therapeutic implications of phosphoproteomics in molecular cancer diagnostics. Utility of [18F]FDG PET/CT in predicting pathological complete response to neoadjuvant therapy in breast cancer: A ...

Microdissection is a method to isolate individual or group of cells from tissue sections. This results in preparation of samples of homogeneous cell types that allows performance of sensitive and ...