Emerging research highlights the transformative potential of m6A RNA modification in the diagnosis and treatment of cardiovascular diseases (CVDs). As the most abundant internal modification of ...

Researchers have shown that a new way of regulating genes is vital for the activity of the nervous system. They found that this form of regulation, a chemical modification on RNA called m6A, is also ...

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the ...

HIV infection of human immune cells triggers a massive increase in methylation, a chemical modification, to both human and viral RNA, aiding replication of the virus. A new study identifies a new ...

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center and the University of Toronto have revealed how a tiny chemical modification in RNA, known as m6A, plays a critical role in the ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

m 6 A modification has been reported to participate in RNA metabolism, predominantly affecting RNA stability. SOCS gene mRNAs have been documented as m 6 A targets in CD4 + T cells, and deletion of ...

The Lai lab uses an integrated approach to study selected topics in mRNA processing and modification, including alternative polyadenylation, circularization and RNA methylation. As a core member of ...

m6A RNA modifications could explain why females have a higher liver fat content than males, with gene therapy being a potential treatment option for liver disease. Non-alcoholic fatty liver can lead ...

Researchers had known for several decades that a certain chemical modification exists on messenger ribonucleic acid (mRNA), which is essential to the flow of genetic information. But only recently did ...