Neutralization assays constitute the definitive means to quantify the functional capacity of antibodies to inhibit SARS-CoV-2 entry into host cells. By assessing how serum or monoclonal antibodies ...

Multiple sublineages of the omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have dominated the coronavirus disease 2019 pandemic since December 2021. BA.5 is currently ...

Biomedical research faces a ubiquitous and fundamental challenge: Because the goal of the research is to improve human health, the human body is logically the best place to perform experiments.

In a recent study published on the medRxiv* preprint server, researchers validate a quick, highly efficient, and automated assay to detect neutralizing antibodies (nAb) against the severe acute ...

The assays allow scientists to measure neutralizing antibodies quickly and efficiently against wild-type and significant variants of SARS-CoV-2 virus. Scientists developing vaccines and therapeutics ...

In a recent study posted to bioRxiv*, researchers evaluated how angiotensin-converting enzyme 2 (ACE2) expression in target cells impacts neutralization. Study: Receptor binding domain (RBD) ...

Circulating Tumor DNA as a Biomarker in Patients With Stage III and IV Wilms Tumor: Analysis From a Children's Oncology Group Trial, AREN0533 Vaccine-induced nAbs are detectable at much lower rates ...

Serum samples obtained from unvaccinated persons after infection with the B.1.1.7 (alpha), B.1.351 (beta), or B.1.617.2 (delta) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ...

The US Food and Drug Administration (FDA) on Wednesday finalized guidance to help industry develop and validate immune assays for the assessment of the immunogenicity of therapeutic protein products ...