Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

Various sayings equate going fast with going alone. But none of them apply to the gene expression journey described by a research team from the University of Göttingen. The team, led by Heike Krebber, ...

What keeps our cells the right size? Scientists have long puzzled over this fundamental question, since cells that are too large or too small are linked to many diseases. Until now, the genetic basis ...

When a gene produces too much protein, it can have devastating consequences on brain development and function. Patients with an overproduction of protein from the chromodomain helicase DNA binding ...

Misshapen proteins cause a mess of trouble—particularly in neurodegenerative diseases. But a new study suggests it's possible ...

Long Noncoding RNAs (LncRNAs) are proven to be critical in cancer biology playing a significant role in tumor formation and ...

Cellular homeostasis and stress response are tightly coordinated processes involving a complex interplay between signaling ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function often depends on its precise three-dimensional structure. A recent study ...

Contrary to historic understanding of RNA’s longevity in cells, some RNAs can persist in cells throughout the life of an organism. Lead authors, Martin Hetzer, PhD, president of the Institute of ...