Cancer-killing T cells have been programmed to have two levels of specificity. First, the T cells have been equipped with a receptor sensitive to a protein that is found only in central nervous system ...

Scientists from the German Cancer Research Center (DKFZ) and the HI-STEM Stem Cell Institute have deciphered a key mechanism ...

When activated by its target, the newly characterized molecule rips the genome apart, a lethal move that researchers can ...

Cells can die naturally from age or disease, but organisms can also actively trigger the death of certain cells when needed. This is known as programmed cell death (PCD), a central biological system ...

Presentations highlight AI-driven mRNA design process enabling up to 40-fold selectivity and 10-fold in vivo oncoselectivity ...

This review highlights the critical role of ubiquitin-specific proteases (USPs) in regulating programmed cell death (PCD) in breast cancer (BC). As the most prevalent malignant tumor among women, BC ...

In a human body, cells are constantly making life-or-death decisions. If they make the wrong choice, the result can be cancer. It may be possible to treat diseases by influencing this behavior. In the ...

There are several programmed cell death pathways that lead to cellular self-destruction, either for developmental processes, tissue maintenance, or stress responses. These include apoptosis, ...

A new kind of CRISPR that destroys cells rather than gene editing them has shown potential for killing sick cells while leaving healthy cells untouched. The technology has largely been tested in cells ...