Virology researchers have found that a specific protein modification to the immune protein MDA5 is key to how our bodies detect and respond to viruses and viral replication. The publication explains ...

A new study on fatty acid acylation, or attachment, patterns onto proteins in Caenorhabditis elegans, a type of roundworm, provides a foundation for future discoveries around protein function and its ...

A research team led by Purdue University’s W. Andy Tao has discovered of a new type of protein modification related to cellular mutation that impairs a crucial enzyme’s ability to help drive energy ...

Exploring the post-translational modifications of a key protein in Parkinson's disease, researchers uncover potential pathways for future therapies in neurodegenerative diseases in general.

N-terminal acetylation represents one of the most ubiquitous protein modifications in eukaryotic cells, with significant implications for protein stability, folding, and interactions. This covalent ...

Scientists have pinpointed the enzyme YcaO as responsible for a rare ribosomal protein modification in several pathogenic bacteria, a process absent in humans. The finding could open new avenues for ...

A research team led by Purdue University’s W. Andy Tao (front) has discovered of a new type of protein modification related to cellular mutation that impairs a crucial enzyme’s ability to help drive ...

Protein palmitoylation and lipid modifications are essential post‐translational processes that regulate protein localisation, stability and function by the covalent attachment of fatty acid chains.

Depression is a debilitating mental health disorder that remains a substantial global health challenge. Despite the availability of various antidepressants, treatment outcomes often face limited ...

Neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, present a significant health challenge, affecting over 50 million people globally. One common feature of these diseases is the ...