Signal transducer and activator of transcription 3 (STAT3) occupies a central node in oncogenic signalling networks. Under normal conditions, STAT3 is activated transiently by phosphorylation on a ...
Schematic diagram of the IL-6/JAK/STAT3 signaling pathway activation in mouse liver macrophages. IRs, inhibitory receptors (IRs); ICIs, immune checkpoint inhibitors; IL-6, interleukin-6; ALT, alanine ...