Neurofibromatosis 2 (NF2) is a rare genetic disorder that causes noncancerous tumors on nerves in the brain and spinal cord. These tumors can affect hearing, vision, and balance. About half of the ...

Neurofibromatosis type 2 is caused by a change in the NF2 gene located on chromosome 22. This gene encodes a protein known as merlin. Mutations in the NF2 gene disrupt the function of merlin, which is ...

Neurofibromatosis type 2 is most often diagnosed based on the presence of physical symptoms that are part of the specific diagnostic criteria for the disorder. Genetic testing for the NF2 mutation is ...

The alternative text for this image may have been generated using AI. This review will discuss the contribution of merlin loss of function in NF2-related tumors and common human cancers and the ...

Safety and Efficacy of CT041 in Patients With Refractory Metastatic Pancreatic Cancer: A Pooled Analysis of Two Early-Phase Trials VEGFR1 and VEGFR2 peptides were injected subcutaneously into ...

On the occasion of World NF2 Awareness Day, the Children's Tumor Foundation has announced the establishment of a significant research initiative dedicated to finding effective treatments for NF2, ...

Neurofibromatosis is a group of rare genetic disorders that cause benign tumors to form on nerve tissue. Tumors in this disorder are usually noncancerous (benign), but can sometimes become cancerous ...

Researchers are recruiting patients for a Phase II clinical trial to test a medication that may slow the progression of Neurofibromatosis Type-2, commonly referred to as NF2. House Research Institute ...