The Lancet | Seminar | Sepsis and septic shock Sepsis commonly interferes with the distribution of systemic blood flow to organ systems via vasodilation and disturbances in microcirculation. Microscopic techniques based on orthogonal polarisation spectral imaging and sidestream dark-field imaging have allowed the acquisition of real-time images of the microcirculation. Image analysis for the quantification of microcirculatory dysfunction has traditionally been done offline, but new software pack
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