Iron isn’t the problem. Metabolizing it is. In histamine intolerance, chronic immune activation alters how iron is absorbed, transported, and utilized even when iron intake is adequate and labs appear “low.” Histamine driven inflammation increases hepcidin, reduces iron mobilization, and impairs iron delivery to tissues. At the same time, copper and ceruloplasmin are both required for iron transport and are often overlooked. This is why: • Ferritin may stay low or stall • Iron supplements don’t
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